In the opening paragraphs of Camus' The Plague Dr. Bernard Rieux spots a dead rat on the landing, the first sign of the plague that is about to sweep the city of Oran. That is how we associate rats in our culture, and have done for hundreds of years. They were assumed to be the bearers of the Black Death of the 14th century that killed an estimated 150 million people in Europe and North Africa. "How now? a rat? Dead, for a ducat, dead!", writes William Shakespeare in Hamlet. "You dirty yellow-bellied rat", James Cagney famously said (and is paraphrased) in the 1932 film "Taxi!". We exclaim "rats!" when things do not go our way, we don't "rat" on our friends, although we might "smell a rat", we can fight "like a cornered rat", and if things are looking bad it's always "the rats that desert the sinking ship", perhaps to avoid "the rat race". We'll need the "The Pied Piper of Hamelin"! Plague-bearing, dirty, unpleasant, selfish, and desperately violent survivalists, we best be rid of them. That is how we, in the Western world, have been brought up to percieve the rat.
Other cultures have a different perspective. From the Vedic tradition, the elephant-headed Hindu god Ganesha, remover of obstacles, has a rat (or mouse) as a mount. It is noted that in part this may represent an impediment to control (the Sanskrit word for mouse is derived from the root to steal) as rodents are a threat to village crops. It also suggests that ability to penetrate the most secret of places. In Rajasthan, in north-western India, there is the Karni Mata Temple also known as "the temple of rats", where 25,000 black rats are revered as reincarnations of the descendents of the Karni Mata the warrior-sage of the 15thC CE.
In south and east Asia where a Lunar calendar is employed, the rat is the first animal of the Chinese zodiac which cycles through a 12-year cycle of animals and the traditional five elements. This past year, from January 25th, 2020 until February 11th, 2021, is the Year of the Metal Rat. The year 2020 is also associated in popular culture with the Cyberpunk roleplaying game which meant, in my mind at least, that this was the Year of the Stainless Steel Rat, recalling the series by the author Harry Harrison. Indeed, in Decmeber I ran a virtual conference with this title which attracted authors, computer security experts, gamers, cultural aficiandos, and politicos from around the world. A publication of proceedings is forthcoming.